HNF‑4α promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis
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چکیده
منابع مشابه
HNF-4α promotes multidrug resistance of gastric cancer cells through the modulation of cell apoptosis
Multidrug resistance (MDR) typically leads to treatment failure, and is associated with disease progression of gastric cancer (GC). In the present study, a total of 15 aberrantly activated transcription factors (TFs) were detected in chemo-resistant GC cells using a TF Activation Profiling Plate Array. Among these TFs, hepatocyte nuclear factor (HNF)-4α was significantly upregulated in multidru...
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ژورنال
عنوان ژورنال: Oncology Letters
سال: 2017
ISSN: 1792-1074,1792-1082
DOI: 10.3892/ol.2017.7095